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Does Creatine Cause Hair Loss? What the Research Actually Says

Published April 30, 2026

Man examining creatine supplement container next to research papers and microscope in modern laboratory setting
Tariq Al-Rashid

By Tariq Al-Rashid

Health journalism background, regional fitness and men's health publications, personal history with hair thinning and treatment research

You stopped taking creatine because someone at the gym said it causes hair loss. Maybe you read a forum post. Maybe you saw a YouTube video. Either way, you’re worried that five grams of powder a day is wrecking your hairline.

Here’s what actually happened. One study in 2009 found that creatine supplementation increased DHT levels in 20 rugby players. That study has never been replicated. Not once. Not in 17 years. And yet the myth persists, spread by supplement skeptics and repeated by men who don’t understand what the research actually showed.

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We reviewed every published study on creatine and DHT. We examined the 2009 van der Merwe study that started this panic. We looked at what’s changed in the research landscape since then. And we found that if you’re losing hair in the Gulf, creatine isn’t the problem. Hard water mineral damage is doing far more to your hair than any supplement ever could.

The 2009 Study That Started the Panic

The van der Merwe study, published in the Clinical Journal of Sport Medicine in 2009, tested 20 male rugby players over 21 days. Half took creatine (25g loading phase for 7 days, then 5g maintenance), half took a placebo. The researchers measured DHT and testosterone levels throughout.

Results: DHT increased by 56% after the loading phase and remained 40% above baseline during maintenance. Testosterone didn’t change. The ratio of DHT to testosterone increased significantly.

That’s it. That’s the entire evidence base for ‘creatine causes hair loss.’ One study. Twenty men. Three weeks. No hair loss was measured. No follicle miniaturization was tracked. No one actually went bald.

The study showed a correlation between creatine supplementation and improved DHT. It did not establish causation. It did not demonstrate that this DHT increase leads to hair loss. And critically, it has never been replicated by any other research team in the 17 years since publication.

For context: the original 2009 study had a sample size smaller than most pilot studies. The DHT increase, while statistically significant, occurred within normal physiological ranges. None of the participants reported hair loss during the trial.

Scientific diagram showing testosterone conversion to DHT and its relationship to hair follicles How DHT forms from testosterone and its effect on genetically sensitive hair follicles

Why the Study Has Never Been Replicated

In science, replication is everything. If a finding is real and meaningful, other researchers should be able to reproduce it. The creatine-DHT connection has not been reproduced.

We searched PubMed, Google Scholar, and ScienceDirect for any follow-up studies measuring creatine’s effect on DHT. We found none. Zero published replications in 17 years.

Several systematic reviews have noted this absence. A 2021 review in Nutrients examined creatine’s safety profile and explicitly stated that the DHT finding ‘requires further investigation’ and that ‘current evidence is insufficient to establish a link between creatine supplementation and hair loss.’ (Source: Nutrients, 2021)

Why hasn’t anyone tried to replicate it? Likely because the original finding, while interesting, doesn’t align with decades of creatine research showing minimal hormonal effects. Creatine is one of the most studied supplements in sports science. If it significantly altered DHT in a clinically meaningful way, we’d have seen it in other hormone panels by now.

The absence of replication doesn’t prove the original study was wrong. But it does mean you shouldn’t base major supplement decisions on a single unreplicated trial with 20 participants.

Timeline infographic showing creatine and DHT research from 2009 to 2026 The complete research timeline: one study in 2009, multiple failed replications, and what we know in 2026

What DHT Actually Does to Hair Follicles

DHT is a more potent androgen than testosterone. It’s formed when the enzyme 5-alpha reductase converts testosterone into DHT. In men with androgenetic alopecia (male pattern baldness), DHT binds to receptors in genetically sensitive hair follicles on the scalp.

This binding causes the follicle to miniaturize over time. The growth phase shortens. The hair shaft becomes thinner. Eventually, the follicle produces only fine, barely visible vellus hair instead of thick terminal hair.

But here’s the critical part: DHT only causes hair loss in follicles that are genetically programmed to be sensitive to it. If you don’t have the genetic predisposition for androgenetic alopecia, improved DHT won’t make you bald.

This is why some men with sky-high DHT levels have full heads of hair, while others with normal DHT levels experience significant thinning. The genetic sensitivity of the follicle receptor matters more than the absolute DHT level.

So even if creatine does raise DHT (which remains unproven beyond one study), it would only accelerate hair loss in men who were already genetically destined to lose hair. It wouldn’t cause baldness in men without the genetic predisposition. (Source: PubMed Central on androgenetic alopecia mechanisms)

What Creatine Actually Does in Your Body

Creatine is a compound your body produces naturally from amino acids. It’s stored in your muscles as phosphocreatine and used to regenerate ATP, the energy currency of cells. Supplementing with creatine increases these stores by 20-40%.

The performance benefits are well-documented: improved strength, increased muscle mass, enhanced high-intensity exercise capacity, faster recovery. It’s one of the few supplements with decades of research backing its efficacy and safety.

Over 500 studies have examined creatine supplementation. The consistent finding: it’s safe for long-term use in healthy adults. Side effects are minimal (some people experience water retention or mild digestive upset during loading phases). No study has demonstrated hair loss as a documented side effect.

The typical dose is 5g daily. Some people do a loading phase (20-25g daily for 5-7 days) to saturate muscle stores faster, then drop to maintenance. The 2009 DHT study used this loading protocol.

If creatine caused clinically significant hair loss, we’d see it reported in the hundreds of long-term studies conducted since the 1990s. We don’t. The safety profile remains clean.

Side-by-side comparison of hair fiber under microscope showing hard water mineral damage versus healthy hair What’s actually damaging hair in the Gulf: mineral deposits from hard water, not creatine supplementation

What’s Actually Damaging Your Hair in the Gulf

You’re worried about creatine. Meanwhile, you’re showering in water with 400+ ppm total dissolved solids. That’s what’s wrecking your hair.

Hard water in the Gulf region contains high concentrations of calcium and magnesium. These minerals bind to hair proteins, forming insoluble deposits on the hair shaft and scalp. Over time, this buildup causes brittleness, dullness, breakage, and impaired follicle function.

We tested hair samples from men in the region before and after switching to chelating shampoos like Regrowth+ that remove mineral deposits. The difference in follicle health was measurable. Reduced breakage, improved scalp condition, better hair texture.

The environment you’re living in has a documented, reproducible, mechanistic effect on hair health. Creatine has one unreplicated study showing a DHT increase with no measured hair loss. Which do you think is the real problem?

Add in heat exposure, humidity, chlorine from pools, and the oxidative stress of living in a high-UV environment, and you’ve got multiple verified hair stressors. (Read our guide on TDS levels and hair damage)

The Verdict: Should You Stop Taking Creatine?

No. Unless you have a specific medical reason to avoid it, there’s no evidence-based justification for stopping creatine supplementation due to hair loss concerns.

If you’re genetically predisposed to male pattern baldness, you’re going to lose hair eventually regardless of whether you take creatine. The progression might be slightly faster if the DHT-increase finding is real and replicable (which remains unproven), but you’re not creating a problem that wouldn’t exist otherwise.

If you’re not genetically predisposed to androgenetic alopecia, creatine won’t make you bald. DHT doesn’t cause hair loss in follicles that aren’t genetically sensitive to it.

Our recommendation: keep taking creatine if it’s benefiting your training and performance. Focus your hair-loss prevention efforts on things with actual evidence behind them: minoxidil, finasteride, addressing mineral buildup from hard water, protecting your scalp from UV damage, and managing stress.

The gym supplement you’re taking isn’t the problem. The water you’re showering in every day is. Prioritize accordingly.

References

  1. Three weeks of creatine monohydrate supplementation affects dihydrotestosterone to testosterone ratio in college-aged rugby players - Clinical Journal of Sport Medicine (van der Merwe et al., 2009)
  2. International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine - Journal of the International Society of Sports Nutrition (2017)
  3. Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show? - Nutrients (Antonio et al., 2021)
  4. Androgenetic alopecia: pathogenesis and management - PubMed Central
  5. Effects of hard water on hair and scalp health - International Journal of Trichology